George Ent (FRS 1663), a distinguished physician, was in Rome in 1636, visited the notable collector Cassiano dal Pozzo and saw his Paper Museum. After he returned to London he carried on a correspondence with Cassiano in letters of more than ordinary interest. Cassiano had sent Ent specimens of fossil wood and a table made from fossil wood. They had come from the estates at Acquasparta belonging to Prince Federico Cesi, the founder of the Accademia dei Lincei. The specimens and the table were shown to early meetings of The Royal Society and had a significant part in the developing debate on the origin of fossils. The letters also record exchanges of books between London and Rome. Among medical matters there is news of William Harvey and his works.